In vivo lability of glucose-6-phosphate dehydrogenase in GdA- and Gdmediterranean deficiency

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In vivo lability of glucose-6-phosphate dehydrogenase in GdA- and GdMediterranean deficiency.

A decreased level of glucose-6-phosphate dehydrogenase might result from decreased rate of synthesis, synthesis of an enzyme of lower catalytic efficiency, increased lability, or a combined mechanism. To test the hypothesis of increased lability, the rate of decline of the enzyme in vivo was measured in three groups of individuals, controls, Gd(-),A-males, and Gd(-), Mediterranean males, by the...

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Prevalence of Glucose-6-phosphate Dehydrogenase (G6PD) Deficiency in Jiroft City in Southern Iran

Background and Aims: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a global problem and the most common cause of jaundice in neonates. Hence, this study was conducted to investigate the prevalence of G6PD deficiency in Jiroft city in southern Kerman. Materials and Methods: This descriptive cross-sectional study was carried out from 2016 to 2019. Blood samples were taken from all patie...

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Hemolysis Induced by Glucose-6-Phosphate Dehydrogenase Deficiency and Its Association with Sex in Children

Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme disorder in human. The aim of this study was to determine the prevalence of G6PD deficiency among children and evaluate its association with ABO/Rh blood groups. Method: Blood samples of 3401 asymptomatic children were analyzed and compared with 317 children who were admitted to hospital because of hemolys...

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Glucose-6-Phosphate Dehydrogenase Deficiency Associated with Thalassemia and Sickle Cell Anemia in an Iranian Family

Sickle cell-thalassemia associated with glucose- 6-phosphate dehydrogenese deficiency is re­ported in an Iranian family. The father had sickle trait and G.6.P.D. deficiency, the mother minor thalassemia, one of the sons siclc:le ceH-thailasemiia., the oth-er sickle cell trait; the daughter had sickle cell-thalassemia and was carrier of G.6.P.D. deficiellcy. 

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1968

ISSN: 0021-9738

DOI: 10.1172/jci105786